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Screening infants with non invasive measurement of oxygen saturation has been proposed as an aid for early detection of duct dependent circulation, but the studies to date have been too small to enable proper estimates of sensitivity,6 7 9 10 11 12 13 and only two studies have included ascertainment of missed cases dying in the community.6 7 An attempt to estimate the sensitivity based on a meta analysis was unsatisfactory because of the merging of studies with different probe sites, different cut off values for saturation, and different oximeters measuring either functional or fractional saturation.14 We evaluated strategies to maximise sensitivity while minimising false positives in a screening test for duct dependent circulation with a new generation oximeter which measured functional oxygen saturation preductally (in right hand) and postductally (in either foot). We arrived at optimal screening cut off values of 3% difference between right hand and foot.15 We also found that the type of oximeter used had a significant effect on both the detection rate and false positive rate.15
“Those would include the Buffett Rule, the capital gains issues, the carried interest issue a host of things that are going to have a potential chilling effect on the economy.”The “Buffett Rule,” first proposed by President Obama in 2011, would impose a minimum 30 percent tax rate on those making more than $1 million per year, whether through earned income or capital gains.
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